Obstetric complications and risk of schizophrenia
These studies investigate environmental and genetic risk factors for schizophrenia using large pregnancy samples from Finland, California, and Philadelphia. The primary goals of these studies are to investigate pre- and perinatal risk factors for schizophrenia.
Psychological symptoms and life events in an undergraduate population
This Temple University College of Liberal Arts Research Award (CLARA)-funded study seeks to investigate whether psychological symptoms commonly experienced in a nonclinical population are differentially associated with a range of psychological disorders, as well as brain structure and function. As part of this study, we are exploring the range of perceptual abnormalities and unusual thought content present in a general population sample, as well as clinical, neurocognitive and environmental correlates with these experiences.
Fetal exposure to maternal stress and inflammation: Effects on neurodevelopment
This National Institute of Mental Health (NIMH) R01 grant-funded study investigates how maternal stress and inflammation during pregnancy as well as fetal hypoxia (lack of oxygen to the fetus) influence the risk of adolescent depression in offspring. We also seek to map trajectories of how these prenatal risk factors result in a cascade of events, leading to altered developmental trajectories in emotional, cognitive, and behavioral outcomes during childhood and subsequent depression during adolescence. This study analyzes maternal interviews and archived sera collected during the 1950s and 1960s within the Kaiser Hospital network in the vicinity of Berkeley, California.